IEDB Prediction IEDB Pred Human I Track Settings

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IEDB Epitope Predictions, Human T-Cell Class I

Configure track container: Immune Epitope Database and Analysis Resource (IEDB) HLA binding predictions

Description

All tracks in this collection (3)

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	Hide Configure	A*01:01	IEDB predicted binding Human HLA T-Cell Class I A*01:01	Data format
	Hide Configure	A*02:01	IEDB predicted binding Human HLA T-Cell Class I A*02:01	Data format
	Hide Configure	A*02:03	IEDB predicted binding Human HLA T-Cell Class I A*02:03	Data format
	Hide Configure	A*02:06	IEDB predicted binding Human HLA T-Cell Class I A*02:06	Data format
	Hide Configure	A*03:01	IEDB predicted binding Human HLA T-Cell Class I A*03:01	Data format
	Hide Configure	A*11:01	IEDB predicted binding Human HLA T-Cell Class I A*11:01	Data format
	Hide Configure	A*23:01	IEDB predicted binding Human HLA T-Cell Class I A*23:01	Data format
	Hide Configure	A*24:02	IEDB predicted binding Human HLA T-Cell Class I A*24:02	Data format
	Hide Configure	A*26:01	IEDB predicted binding Human HLA T-Cell Class I A*26:01	Data format
	Hide Configure	A*30:01	IEDB predicted binding Human HLA T-Cell Class I A*30:01	Data format
	Hide Configure	A*30:02	IEDB predicted binding Human HLA T-Cell Class I A*30:02	Data format
	Hide Configure	A*31:01	IEDB predicted binding Human HLA T-Cell Class I A*31:01	Data format
	Hide Configure	A*32:01	IEDB predicted binding Human HLA T-Cell Class I A*32:01	Data format
	Hide Configure	A*33:01	IEDB predicted binding Human HLA T-Cell Class I A*33:01	Data format
	Hide Configure	A*68:01	IEDB predicted binding Human HLA T-Cell Class I A*68:01	Data format
	Hide Configure	A*68:02	IEDB predicted binding Human HLA T-Cell Class I A*68:02	Data format
	Hide Configure	B*07:02	IEDB predicted binding Human HLA T-Cell Class I B*07:02	Data format
	Hide Configure	B*08:01	IEDB predicted binding Human HLA T-Cell Class I B*08:01	Data format
	Hide Configure	B*15:01	IEDB predicted binding Human HLA T-Cell Class I B*15:01	Data format
	Hide Configure	B*35:01	IEDB predicted binding Human HLA T-Cell Class I B*35:01	Data format
	Hide Configure	B*40:01	IEDB predicted binding Human HLA T-Cell Class I B*40:01	Data format
	Hide Configure	B*44:02	IEDB predicted binding Human HLA T-Cell Class I B*44:02	Data format
	Hide Configure	B*44:03	IEDB predicted binding Human HLA T-Cell Class I B*44:03	Data format
	Hide Configure	B*51:01	IEDB predicted binding Human HLA T-Cell Class I B*51:01	Data format
	Hide Configure	B*53:01	IEDB predicted binding Human HLA T-Cell Class I B*53:01	Data format
	Hide Configure	B*57:01	IEDB predicted binding Human HLA T-Cell Class I B*57:01	Data format
	Hide Configure	B*58:01	IEDB predicted binding Human HLA T-Cell Class I B*58:01	Data format

Assembly: Ebola virus Sierra Leone 2014 (G3683/KM034562.1/eboVir3)

Description

This track shows peptides that are predicted to be displayed by human class I MHCs.

Display Conventions and Configuration

Peptides are shaded by IC50 values and split into subtracks by HLA-alleles.

Methods

For human epitope prediction, binding affinity for all possible 9-mer peptides from each protein sequence to a set of 27 HLA alleles that are most frequent in the global population, using the SMM method available in the IEDB MHC class I binding prediction tool. All peptides with predicted binding affinity (expressed as IC50 nM) below previously optimized allele-specific thresholds were selected as predicted binders. In the case of rhesus macaque class I T cell epitope prediction, the binding affinity of all 9-mer peptides was predicted for a total of 19 alleles (7 Indian and 12 Chinese rhesus macaques) that are most frequent in these species. The binding affinity predictions utilized the "IEDB recommended" method from the IEDB MHC class I binding prediction tool. Peptides with the IEDB consensus percentile rank <= 1.0 were selected. Lower values for either IC50 or percentile rank indicate stronger binding.