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MaveDB Experiments Tracks
 
Heatmaps and Alignment for MaveDB tracks   (All Expression tracks)

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MaveDB Alignments  MaveDB Experiment Sequence Alignments  
 MaveDB Heatmaps  Variant Effect Maps from MaveDB  

Assembly: Human Dec. 2013 (GRCh38/hg38)

Description

This supertrack provides heatmaps of multiplexed assays of variant effects (MAVE) from MaveDB. Each heatmap presents the results of an experiment where many small substitutions were tested within a gene to examine their functional consequences. Accompanying tracks display alignments of each experiment sequence to the genome.

Data Access

Direct access to the data files for these experiments can be obtained from MaveDB.

References

Rubin AF, Stone J, Bianchi AH, Capodanno BJ, Da EY, Dias M, Esposito D, Frazer J, Fu Y, Grindstaff SB et al. MaveDB 2024: a curated community database with over seven million variant effects from multiplexed functional assays. Genome Biol. 2025 Jan 21;26(1):13. PMID: 39838450; PMC: PMC11753097